Neuro-Modulated Hebbian Learning for Fully Test-Time Adaptation

Yushun Tang, Ce Zhang, Heng Xu, Shuoshuo Chen, Jie Cheng +3 more
2/14/2026

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Abstract

Fully test-time adaptation aims to adapt the network model based on sequential analysis of input samples during the inference stage to address the cross-domain performance degradation problem of deep neural networks. We take inspiration from the biological plausibility learning where the neuron responses are tuned based on a local synapse-change procedure and activated by competitive lateral inhibition rules. Based on these feed-forward learning rules, we design a soft Hebbian learning process which provides an unsupervised and effective mechanism for online adaptation. We observe that the performance of this feed-forward Hebbian learning for fully test-time adaptation can be significantly improved by incorporating a feedback neuromodulation layer. It is able to fine-tune the neuron responses based on the external feedback generated by the error backpropagation from the top inference layers. This leads to our proposed neuro-modulated Hebbian learning (NHL) method for fully test-time adaptation. With the unsupervised feed-forward soft Hebbian learning being combined with a learned neuromodulator to capture feedback from external responses, the source model can be effectively adapted during the testing process. Experimental results on benchmark datasets demonstrate that our proposed method can significantly improve the adaptation performance of network models and outperforms existing state-of-the-art methods.

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Cite this paper

@article{tang2026neuromodulated,
  title  = {Neuro-Modulated Hebbian Learning for Fully Test-Time Adaptation},
  author = {Yushun Tang and Ce Zhang and Heng Xu and Shuoshuo Chen and Jie Cheng and Luziwei Leng and Qinghai Guo and Zhihai He},
  year   = {2026},
  eprint = {2303.00914},
  archivePrefix = {arXiv},
  url    = {https://arxiv.org/pdf/2303.00914},
  journal = {CVPR 2023 2023}
}

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