MRI-CORE: A Foundation Model for Magnetic Resonance Imaging

Haoyu Dong, Yuwen Chen, Hanxue Gu, Nicholas Konz, Yaqian Chen +2 more
6/13/2025
eess.IVcs.AIcs.CV

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Abstract

The widespread use of Magnetic Resonance Imaging (MRI) in combination with deep learning shows promise for many high-impact automated diagnostic and prognostic tools. However, training new models requires large amounts of labeled data, a challenge due to high cost of precise annotations and data privacy. To address this issue, we introduce the MRI-CORE, a vision foundation model trained using more than 6 million slices from over 110 thousand MRI volumes across 18 body locations. Our experiments show notable improvements in performance over state-of-the-art methods in 13 data-restricted segmentation tasks, as well as in image classification, and zero-shot segmentation, showing the strong potential of MRI-CORE to enable data-efficient development of artificial intelligence models. We also present data on which strategies yield most useful foundation models and a novel analysis relating similarity between pre-training and downstream task data with transfer learning performance. Our model is publicly available with a permissive license.

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@article{dong2025mricore,
  title  = {MRI-CORE: A Foundation Model for Magnetic Resonance Imaging},
  author = {Haoyu Dong and Yuwen Chen and Hanxue Gu and Nicholas Konz and Yaqian Chen and Qihang Li and Maciej A. Mazurowski},
  year   = {2025},
  eprint = {2506.12186},
  archivePrefix = {arXiv},
  url    = {http://arxiv.org/abs/2506.12186v2}
}

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