Gazal-R1: Achieving State-of-the-Art Medical Reasoning with Parameter-Efficient Two-Stage Training

Ahmed M. Adly, Mostafa Samy, Amr Fawzy
6/18/2025
cs.CL

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Abstract

We present Gazal-R1, a 32-billion-parameter language model that achieves state-of-the-art performance in medical reasoning while providing transparent, step-by-step explanations for clinical decision-making. Built upon Qwen3 32B, our model demonstrates that strategic training can enable mid-sized models to outperform significantly larger counterparts in specialized domains. We developed a novel two-stage training pipeline: first, supervised fine-tuning on a carefully curated dataset of 107,033 synthetic medical reasoning examples that teaches structured clinical thinking, enhanced by advanced parameter-efficient techniques including Weight-Decomposed Low-Rank Adaptation (DoRA) and Rank-Stabilized LoRA (rsLoRA); second, reinforcement learning using Group Relative Policy Optimization (GRPO) with a sophisticated multi-component reward system that refines accuracy, format adherence, and reasoning quality. Gazal-R1 achieves exceptional performance across medical benchmarks, scoring 87.1% on MedQA, 81.6% on MMLU Pro (Medical), and 79.6% on PubMedQA, surpassing models up to 12x larger. Beyond its strong empirical results, this work provides detailed insights into the challenges of training reasoning-capable models in specialized domains, including issues with reward hacking, training instability, and the fundamental tension between factual recall and detailed reasoning. Our methodology offers a reproducible framework for developing high-capability, domain-specific language models that balance performance, efficiency, and explainability.

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Cite this paper

@article{adly2025gazalr,
  title  = {Gazal-R1: Achieving State-of-the-Art Medical Reasoning with Parameter-Efficient Two-Stage Training},
  author = {Ahmed M. Adly and Mostafa Samy and Amr Fawzy},
  year   = {2025},
  eprint = {2506.21594},
  archivePrefix = {arXiv},
  url    = {http://arxiv.org/abs/2506.21594v1}
}

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