MIDOG 2025: Mitotic Figure Detection with Attention-Guided False Positive Correction

Abstract

We present a novel approach which extends the existing Fully Convolutional One-Stage Object Detector (FCOS) for mitotic figure detection. Our composite model adds a Feedback Attention Ladder CNN (FAL-CNN) model for classification of normal versus abnormal mitotic figures, feeding into a fusion network that is trained to generate adjustments to bounding boxes predicted by FCOS. Our network aims to reduce the false positive rate of the FCOS object detector, to improve the accuracy of object detection and enhance the generalisability of the network. Our model achieved an F1 score of 0.655 for mitosis detection on the preliminary evaluation dataset.