FHIR-RAG-MEDS: Integrating HL7 FHIR with Retrieval-Augmented Large Language Models for Enhanced Medical Decision Support

Yildiray Kabak, Gokce B. Laleci Erturkmen, Mert Gencturk, Tuncay Namli, A. Anil Sinaci +4 more
9/9/2025
cs.AI

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Abstract

In this study, we propose FHIR-RAG-MEDS system that aims to integrate Health Level 7 Fast Healthcare Interoperability Resources (HL7 FHIR) with a Retrieval-Augmented Generation (RAG)-based system to improve personalized medical decision support on evidence-based clinical guidelines, emphasizing the need for research in practical applications. In the evolving landscape of medical decision support systems, integrating advanced technologies such as RAG and HL7 FHIR can significantly enhance clinical decision-making processes. Despite the potential of these technologies, there is limited research on their integration in practical applications.

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Cite this paper

@article{kabak2025fhirragmeds,
  title  = {FHIR-RAG-MEDS: Integrating HL7 FHIR with Retrieval-Augmented Large Language Models for Enhanced Medical Decision Support},
  author = {Yildiray Kabak and Gokce B. Laleci Erturkmen and Mert Gencturk and Tuncay Namli and A. Anil Sinaci and Ruben Alcantud Corcoles and Cristina Gomez Ballesteros and Pedro Abizanda and Asuman Dogac},
  year   = {2025},
  eprint = {2509.07706},
  archivePrefix = {arXiv},
  url    = {http://arxiv.org/abs/2509.07706v2}
}

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