Embodied sensorimotor control: computational modeling of the neural control of movement

Abstract

We review how sensorimotor control is dictated by interacting neural populations, optimal feedback mechanisms, and the biomechanics of bodies. First, we outline the distributed anatomical loops that shuttle sensorimotor signals between cortex, subcortical regions, and spinal cord. We then summarize evidence that neural population activity occupies low-dimensional, dynamically evolving manifolds during planning and execution of movements. Next, we summarize literature explaining motor behavior through the lens of optimal control theory, which clarifies the role of internal models and feedback during motor control. Finally, recent studies on embodied sensorimotor control address gaps within each framework by aiming to elucidate neural population activity through the explicit control of musculoskeletal dynamics. We close by discussing open problems and opportunities: multi-tasking and cognitively rich behavior, multi-regional circuit models, and the level of anatomical detail needed in body and network models. Together, this review and recent advances point towards reaching an integrative account of the neural control of movement.