Designing a Convolutional Neural Network for High-Accuracy Oral Cavity Squamous Cell Carcinoma (OCSCC) Detection

Abstract

Oral Cavity Squamous Cell Carcinoma (OCSCC) is the most common type of head and neck cancer. Due to the subtle nature of its early stages, deep and hidden areas of development, and slow growth, OCSCC often goes undetected, leading to preventable deaths. However, properly trained Convolutional Neural Networks (CNNs), with their precise image segmentation techniques and ability to apply kernel matrices to modify the RGB values of images for accurate image pattern recognition, would be an effective means for early detection of OCSCC. Pairing this neural network with image capturing and processing hardware would allow increased efficacy in OCSCC detection. The aim of our project is to develop a Convolutional Neural Network trained to recognize OCSCC, as well as to design a physical hardware system to capture and process detailed images, in order to determine the image quality required for accurate predictions. A CNN was trained on 4293 training images consisting of benign and malignant tumors, as well as negative samples, and was evaluated for its precision, recall, and Mean Average Precision (mAP) in its predictions of OCSCC. A testing dataset of randomly assorted images of cancerous, non-cancerous, and negative images was chosen, and each image was altered to represent 5 common resolutions. This test data set was thoroughly analyzed by the CNN and predictions were scored on the basis of accuracy. The designed enhancement hardware was used to capture detailed images, and its impact was scored. An application was developed to facilitate the testing process and bring open access to the CNN. Images of increasing resolution resulted in higher-accuracy predictions on a logarithmic scale, demonstrating the diminishing returns of higher pixel counts.