A Women's Health Benchmark for Large Language Models

Victoria-Elisabeth Gruber, Razvan Marinescu, Diego Fajardo, Amin H. Nassar, Christopher Arkfeld +11 more
12/18/2025
cs.CLcs.AIcs.LG

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Abstract

As large language models (LLMs) become primary sources of health information for millions, their accuracy in women's health remains critically unexamined. We introduce the Women's Health Benchmark (WHB), the first benchmark evaluating LLM performance specifically in women's health. Our benchmark comprises 96 rigorously validated model stumps covering five medical specialties (obstetrics and gynecology, emergency medicine, primary care, oncology, and neurology), three query types (patient query, clinician query, and evidence/policy query), and eight error types (dosage/medication errors, missing critical information, outdated guidelines/treatment recommendations, incorrect treatment advice, incorrect factual information, missing/incorrect differential diagnosis, missed urgency, and inappropriate recommendations). We evaluated 13 state-of-the-art LLMs and revealed alarming gaps: current models show approximately 60\% failure rates on the women's health benchmark, with performance varying dramatically across specialties and error types. Notably, models universally struggle with "missed urgency" indicators, while newer models like GPT-5 show significant improvements in avoiding inappropriate recommendations. Our findings underscore that AI chatbots are not yet fully able of providing reliable advice in women's health.

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@article{gruber2025womens,
  title  = {A Women's Health Benchmark for Large Language Models},
  author = {Victoria-Elisabeth Gruber and Razvan Marinescu and Diego Fajardo and Amin H. Nassar and Christopher Arkfeld and Alexandria Ludlow and Shama Patel and Mehrnoosh Samaei and Valerie Klug and Anna Huber and Marcel Gühner and Albert Botta i Orfila and Irene Lagoja and Kimya Tarr and Haleigh Larson and Mary Beth Howard},
  year   = {2025},
  eprint = {2512.17028},
  archivePrefix = {arXiv},
  url    = {http://arxiv.org/abs/2512.17028v1}
}

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