LENS: LLM-Enabled Narrative Synthesis for Mental Health by Aligning Multimodal Sensing with Language Models

Wenxuan Xu, Arvind Pillai, Subigya Nepal, Amanda C Collins, Daniel M Mackin +4 more
12/28/2025
cs.CLcs.AI

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Abstract

Multimodal health sensing offers rich behavioral signals for assessing mental health, yet translating these numerical time-series measurements into natural language remains challenging. Current LLMs cannot natively ingest long-duration sensor streams, and paired sensor-text datasets are scarce. To address these challenges, we introduce LENS, a framework that aligns multimodal sensing data with language models to generate clinically grounded mental-health narratives. LENS first constructs a large-scale dataset by transforming Ecological Momentary Assessment (EMA) responses related to depression and anxiety symptoms into natural-language descriptions, yielding over 100,000 sensor-text QA pairs from 258 participants. To enable native time-series integration, we train a patch-level encoder that projects raw sensor signals directly into an LLM's representation space. Our results show that LENS outperforms strong baselines on standard NLP metrics and task-specific measures of symptom-severity accuracy. A user study with 13 mental-health professionals further indicates that LENS-produced narratives are comprehensive and clinically meaningful. Ultimately, our approach advances LLMs as interfaces for health sensing, providing a scalable path toward models that can reason over raw behavioral signals and support downstream clinical decision-making.

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Cite this paper

@article{xu2025lens,
  title  = {LENS: LLM-Enabled Narrative Synthesis for Mental Health by Aligning Multimodal Sensing with Language Models},
  author = {Wenxuan Xu and Arvind Pillai and Subigya Nepal and Amanda C Collins and Daniel M Mackin and Michael V Heinz and Tess Z Griffin and Nicholas C Jacobson and Andrew Campbell},
  year   = {2025},
  eprint = {2512.23025},
  archivePrefix = {arXiv},
  url    = {http://arxiv.org/abs/2512.23025v1}
}

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