On The Robustness of Foundational 3D Medical Image Segmentation Models Against Imprecise Visual Prompts

Soumitri Chattopadhyay, Basar Demir, Marc Niethammer
1/23/2026
eess.IVcs.CV

Official code: ucsdbiag/Prompt-Robustness-MedSegFMs (0 stars, last commit 2026-04-06).

Abstract

While 3D foundational models have shown promise for promptable segmentation of medical volumes, their robustness to imprecise prompts remains under-explored. In this work, we aim to address this gap by systematically studying the effect of various controlled perturbations of dense visual prompts, that closely mimic real-world imprecision. By conducting experiments with two recent foundational models on a multi-organ abdominal segmentation task, we reveal several facets of promptable medical segmentation, especially pertaining to reliance on visual shape and spatial cues, and the extent of resilience of models towards certain perturbations. Codes are available at: https://github.com/ucsdbiag/Prompt-Robustness-MedSegFMs

View on arXivView PDF

Code Implementations(1)

[ISBI 2026, Oral] On The Robustness of Foundational 3D Medical Image Segmentation Models Against Imprecise Visual Prompts

01Shell, PythonNov 1, 20256 months ago

Similar Papers

Cite this paper

@article{chattopadhyay2026robustness,
  title  = {On The Robustness of Foundational 3D Medical Image Segmentation Models Against Imprecise Visual Prompts},
  author = {Soumitri Chattopadhyay and Basar Demir and Marc Niethammer},
  year   = {2026},
  eprint = {2601.16383},
  archivePrefix = {arXiv},
  url    = {http://arxiv.org/abs/2601.16383v1}
}

Add a badge to your README

Shows whether official code is linked for this paper.

Code of Paper badge
[![Code of Paper](https://codeofpaper.com/badge/2601.16383.svg)](https://codeofpaper.com/paper/2601.16383)

Discussion