Pancake: Hierarchical Memory System for Multi-Agent LLM Serving

Zhengding Hu, Zaifeng Pan, Prabhleen Kaur, Vibha Murthy, Zhongkai Yu +4 more
2/25/2026
cs.MA

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Abstract

In this work, we identify and address the core challenges of agentic memory management in LLM serving, where large-scale storage, frequent updates, and multiple coexisting agents jointly introduce complex and high-cost approximate nearest neighbor (ANN) searching problems. We present Pancake, a multi-tier agentic memory system that unifies three key techniques: (i) multi-level index caching for single agents, (ii) coordinated index management across multiple agents, and (iii) collaborative GPU-CPU acceleration. Pancake exposes easy-to-use interface that can be integrated into memory-based agents like Mem-GPT, and is compatible with agentic frameworks such as LangChain and LlamaIndex. Experiments on realistic agent workloads show that Pancake substantially outperforms existing frameworks, achieving more than 4.29x end-to-end throughput improvement.

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Cite this paper

@article{hu2026pancake,
  title  = {Pancake: Hierarchical Memory System for Multi-Agent LLM Serving},
  author = {Zhengding Hu and Zaifeng Pan and Prabhleen Kaur and Vibha Murthy and Zhongkai Yu and Yue Guan and Zhen Wang and Steven Swanson and Yufei Ding},
  year   = {2026},
  eprint = {2602.21477},
  archivePrefix = {arXiv},
  url    = {http://arxiv.org/abs/2602.21477v1}
}

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