Sparking Scientific Creativity via LLM-Driven Interdisciplinary Inspiration

Priyanka Kargupta, Shuhaib Mehri, Dilek Hakkani-Tur, Jiawei Han
3/12/2026
cs.CLcs.AI

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Abstract

Despite interdisciplinary research leading to larger and longer-term impact, most work remains confined to single-domain academic silos. Recent AI-based approaches to scientific discovery show promise for interdisciplinary research, but many prioritize rapidly designing experiments and solutions, bypassing the exploratory, collaborative reasoning processes that drive creative interdisciplinary breakthroughs. As a result, prior efforts largely prioritize automating scientific discovery rather than augmenting the reasoning processes that underlie scientific disruption. We present Idea-Catalyst, a novel framework that systematically identifies interdisciplinary insights to support creative reasoning in both humans and large language models. Starting from an abstract research goal, Idea-Catalyst is designed to assist the brainstorming stage, explicitly avoiding premature anchoring on specific solutions. The framework embodies key metacognitive features of interdisciplinary reasoning: (a) defining and assessing research goals, (b) awareness of a domain's opportunities and unresolved challenges, and (c) strategic exploration of interdisciplinary ideas based on impact potential. Concretely, Idea-Catalyst decomposes an abstract goal (e.g., improving human-AI collaboration) into core target-domain research questions that guide the analysis of progress and open challenges within that domain. These challenges are reformulated as domain-agnostic conceptual problems, enabling retrieval from external disciplines (e.g., Psychology, Sociology) that address analogous issues. By synthesizing and recontextualizing insights from these domains back into the target domain, Idea-Catalyst ranks source domains by their interdisciplinary potential. Empirically, this targeted integration improves average novelty by 21% and insightfulness by 16%, while remaining grounded in the original research problem.

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Cite this paper

@article{kargupta2026sparking,
  title  = {Sparking Scientific Creativity via LLM-Driven Interdisciplinary Inspiration},
  author = {Priyanka Kargupta and Shuhaib Mehri and Dilek Hakkani-Tur and Jiawei Han},
  year   = {2026},
  eprint = {2603.12226},
  archivePrefix = {arXiv},
  url    = {http://arxiv.org/abs/2603.12226v1}
}

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