Understand and Accelerate Memory Processing Pipeline for Disaggregated LLM Inference

Zifan He, Rui Ma, Yizhou Sun, Jason Cong
3/30/2026
cs.DCcs.AI

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Abstract

Modern large language models (LLMs) increasingly depends on efficient long-context processing and generation mechanisms, including sparse attention, retrieval-augmented generation (RAG), and compressed contextual memory, to support complex reasoning. We show that these optimizations can be unified into a four-step memory processing pipeline: Prepare Memory, Compute Relevancy, Retrieval, and Apply to Inference. Through systematic profiling, we identify a 22%-97% memory processing overhead in LLM inference and strong heterogeneity in its computational characteristics. Motivated by this insight, we argue that \textbf{heterogeneous systems} are well-suited to accelerate memory processing and thus end-to-end inference. We demonstrate this approach on a GPU-FPGA system by offloading sparse, irregular, and memory-bounded operations to FPGAs while retaining compute-intensive operations on GPUs. Evaluated on an AMD MI210 GPU and an Alveo U55C FPGA, our system is $1.04\sim2.2\times$ faster and requires $1.11\sim4.7\times$ less energy across multiple LLM inference optimizations than the GPU baseline (similar results hold on NVIDIA A100). These results establish heterogeneous systems as a practical direction for efficient LLM memory processing and inform future heterogeneous hardware design.

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Cite this paper

@article{he2026understand,
  title  = {Understand and Accelerate Memory Processing Pipeline for Disaggregated LLM Inference},
  author = {Zifan He and Rui Ma and Yizhou Sun and Jason Cong},
  year   = {2026},
  eprint = {2603.29002},
  archivePrefix = {arXiv},
  url    = {http://arxiv.org/abs/2603.29002v1}
}

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