Depression Risk Assessment in Social Media via Large Language Models

Giorgia Gulino, Manuel Petrucci
4/21/2026
cs.CLcs.AI

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Abstract

Depression is one of the most prevalent and debilitating mental health conditions worldwide, frequently underdiagnosed and undertreated. The proliferation of social media platforms provides a rich source of naturalistic linguistic signals for the automated monitoring of psychological well-being. In this work, we propose a system based on Large Language Models (LLMs) for depression risk assessment in Reddit posts, through multi-label classification of eight depression-associated emotions and the computation of a weighted severity index. The method is evaluated in a zero-shot setting on the annotated DepressionEmo dataset (~6,000 posts) and applied in-the-wild to 469,692 comments collected from four subreddits over the period 2024-2025. Our best model, gemma3:27b, achieves micro-F1 = 0.75 and macro-F1 = 0.70, results competitive with purpose-built fine-tuned models (BART: micro-F1 = 0.80, macro-F1 = 0.76). The in-the-wild analysis reveals consistent and temporally stable risk profiles across communities, with marked differences between r/depression and r/anxiety. Our findings demonstrate the feasibility of a cost-effective, scalable approach for large-scale psychological monitoring.

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@article{gulino2026depression,
  title  = {Depression Risk Assessment in Social Media via Large Language Models},
  author = {Giorgia Gulino and Manuel Petrucci},
  year   = {2026},
  eprint = {2604.19887},
  archivePrefix = {arXiv},
  url    = {http://arxiv.org/abs/2604.19887v1}
}

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