Are LLMs Ready to Assist Physicians? PhysAssistBench for Interactive Doctor-Patient-EHR Assistance

Tianming Du, Peijie Yu, Sihan Shang, Danli Shi, My Linh Nguyen +10 more
6/17/2026
cs.CLcs.AI

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Abstract

The most plausible near-term role of medical LLMs is to assist rather than replace physicians, yet current evaluations often test isolated capabilities: clinical knowledge, EHR system interaction, or patient communication. Physician assistance instead requires coordinating these capabilities within the same interaction, where physicians issue underspecified requests, patients describe symptoms ambiguously, and EHR systems demand precise tool use. We introduce PhysAssistBench, a benchmark for interactive doctor-patient-EHR assistance. Built from real MIMIC-IV cases, PhysAssistBench uses a scalable pipeline to construct agentic patients: interactive, record-grounded agents that turn static EHR records into multi-turn clinical scenarios while preserving clinical factuality. PhysAssistBench provides a curated bilingual evaluation set of 1,296 manually reviewed and physician-validated turns. Experiments with leading LLMs show that current models remain unreliable in this setting, which exposes a key bottleneck for clinical LLMs: reliable assistance requires coordination across knowledge, communication, and systems, not isolated gains in any of them.

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Cite this paper

@article{du2026llms,
  title  = {Are LLMs Ready to Assist Physicians? PhysAssistBench for Interactive Doctor-Patient-EHR Assistance},
  author = {Tianming Du and Peijie Yu and Sihan Shang and Danli Shi and My Linh Nguyen and Shengbo Gao and Guangyuan Li and Yinghong Yu and Yan Jiang and Qianlong Zhao and Behzad Bozorgtabar and Shaoxiong Ji and Jiazhen Pan and Daniel Rueckert and Jiancheng Yang},
  year   = {2026},
  eprint = {2606.18613},
  archivePrefix = {arXiv},
  url    = {http://arxiv.org/abs/2606.18613v2}
}

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