BrainAgent: A Large Language Model-Driven Multi-Agent Framework for Autonomous Brain Signal Understanding

Yangxuan Zhou, Sha Zhao, Jiquan Wang, Shijian Li, Gang Pan
6/24/2026
cs.AI

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Abstract

Brain-Computer Interfaces (BCIs) and brain signal understanding are pivotal for clinical health and next-generation interactions. Despite this significance, its widespread adoption in real-world scenarios remains restricted, primarily because current analytical paradigms lack sufficient agentic intelligence. First, existing methodologies impose prohibitive technical barriers, requiring extensive specialized expertise. Second, they remain inherently static and task-specific, failing to execute the complex, long-horizon workflows essential for real-world deployment. To accelerate the democratization of brain signal understanding, we draw inspiration from Large Language Models (LLMs) to introduce BrainAgent, an LLM-driven multi-agent framework designed to ground abstract natural language intent into rigorous, executable, and end-to-end processing pipelines. BrainAgent employs a hierarchical architecture where a central supervisor orchestrates specialized sub-agents for adaptive task decomposition and execution. Furthermore, we establish a comprehensive, systematic benchmark for evaluating agentic systems in brain signal analysis. Empirical results demonstrate that BrainAgent effectively automates complex workflows with superior reliability, marking a paradigm shift toward democratized brain signal understanding.

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@article{zhou2026brainagent,
  title  = {BrainAgent: A Large Language Model-Driven Multi-Agent Framework for Autonomous Brain Signal Understanding},
  author = {Yangxuan Zhou and Sha Zhao and Jiquan Wang and Shijian Li and Gang Pan},
  year   = {2026},
  eprint = {2606.25400},
  archivePrefix = {arXiv},
  url    = {http://arxiv.org/abs/2606.25400v1}
}

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