Impact of Data Augmentation on Confidence Calibration in Melanoma Classification

Morgan May, Simon Caton, Pierpaolo Dondio
10/5/2026
cs.AIcs.CVcs.LG

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Abstract

Accurately quantifying the predictive uncertainty or improving model calibration plays an important role in medical image classification, in particular in melanoma diagnosis, where accurate uncertainty quantification can have significant implications for patient care. One of the methods for calibration improvement is data augmentation. In addition, data augmentation as a method for synthetically increasing the size of the dataset has been proven to improve the performance of models trained on imbalanced datasets. However, the impact of data augmentation, as a transformation of a part of the original data, on calibration of models trained on imbalanced datasets, in particular in melanoma classification is under-explored. We train neural networks on SIIM-ISIC 2020 melanoma classification dataset under two conditions: with and without data augmentation, and compare the differences in AUC and expected calibration error (ECE) in both scenarios. Our results shows improvements in uncertainty calibration using different augmentation methods.

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@article{may2026impact,
  title  = {Impact of Data Augmentation on Confidence Calibration in Melanoma Classification},
  author = {Morgan May and Simon Caton and Pierpaolo Dondio},
  year   = {2026},
  eprint = {2610.06146},
  archivePrefix = {arXiv},
  url    = {http://arxiv.org/abs/2610.06146v1}
}

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