Beyond Report Imitation: Clinically Aware Multi-Image Ultrasound Report Generation from Visible Evidence

Abstract

Generating ultrasound reports from multiple images requires aggregating clinical evidence across views, yet archived key frames capture only part of the dynamic examination. Raw-report imitation is therefore misaligned with visual supervision: content that is clinically valid for the full examination may be unverifiable from the images available to a model. This gap creates a clinical behavior alignment problem. A model must preserve visible findings, avoid diagnostic reversals and unsupported completion, and not collapse into conservative templates. We propose CAMEO, a Clinically Aware Multi-image Evidence-grounded Orchestration framework for ultrasound report generation. Stage I learns ultrasound visual-language primitives; Stage II performs Cross-View Evidence Grounding by distilling trusted visible report points into multi-image QA and report-style supervision; and Stage III performs Clinically Aware Preference Alignment using clinical-error-oriented preference pairs. From USReport, we construct USReport-Distilled with 17,670 evidence-grounded paired-image training instances and USReport-Pref with 21,869 preference pairs; we additionally use 25,631 PubMedVision-US ultrasound instruction samples for domain adaptation and multi-image instruction tuning. On the primary USReport-Distilled benchmark, CAMEO improves over EchoVLM from 0.25 to 0.40 BLEU-1, 0.28 to 0.45 ROUGE-1, and 0.27 to 0.43 METEOR, while raising ClinicalScore from 55.02 to 74.20. These results underscore the value of evidence-grounded supervision, clinically aware alignment, and clinically structured evaluation for reliable ultrasound report generation.