HotProtein: A Novel Framework for Protein Thermostability Prediction and Editing

Tianlong Chen, Chengyue Gong, Daniel J. Diaz, Xuxi Chen, Jordan Wells +5 more
2/12/2026

No official code found. Best implementation: VITA-Group/HotProtein (32 stars, MIT, last commit 2023-03-19).

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MIT

[ICLR 2023] "HotProtein: A Novel Framework for Protein Thermostability Prediction and Editing" by Tianlong Chen*, Chengyue Gong*, Daniel Jesus Diaz, Xuxi Chen, Jordan Tyler Wells, Qiang Liu, Zhangyang Wang, Andrew Ellington, Alex Dimakis, Adam Klivans

325Shell, PythonJan 29, 20233 years agoMIT

Cite this paper

@article{chen2026hotprotein,
  title  = {HotProtein: A Novel Framework for Protein Thermostability Prediction and Editing},
  author = {Tianlong Chen and Chengyue Gong and Daniel J. Diaz and Xuxi Chen and Jordan Wells and Qiang Liu and Zhangyang Wang and A. Ellington and Alex Dimakis and Adam R. Klivans},
  year   = {2026},
  url    = {https://api.semanticscholar.org/CorpusID:e36dfa8078c211ca9420f86b0dff2480150d5374},
  journal = {ICLR 2023 2023}
}

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