Exploring LLMs for Scientific Information Extraction Using The SciEx Framework

Sha Li, Ayush Sadekar, Nathan Self, Yiqi Su, Lars Andersland +8 more
12/10/2025
cs.AIcs.CL

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Abstract

Large language models (LLMs) are increasingly touted as powerful tools for automating scientific information extraction. However, existing methods and tools often struggle with the realities of scientific literature: long-context documents, multi-modal content, and reconciling varied and inconsistent fine-grained information across multiple publications into standardized formats. These challenges are further compounded when the desired data schema or extraction ontology changes rapidly, making it difficult to re-architect or fine-tune existing systems. We present SciEx, a modular and composable framework that decouples key components including PDF parsing, multi-modal retrieval, extraction, and aggregation. This design streamlines on-demand data extraction while enabling extensibility and flexible integration of new models, prompting strategies, and reasoning mechanisms. We evaluate SciEx on datasets spanning three scientific topics for its ability to extract fine-grained information accurately and consistently. Our findings provide practical insights into both the strengths and limitations of current LLM-based pipelines.

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Cite this paper

@article{li2025exploring,
  title  = {Exploring LLMs for Scientific Information Extraction Using The SciEx Framework},
  author = {Sha Li and Ayush Sadekar and Nathan Self and Yiqi Su and Lars Andersland and Mira Chaplin and Annabel Zhang and Hyoju Yang and James B Henderson and Krista Wigginton and Linsey Marr and T. M. Murali and Naren Ramakrishnan},
  year   = {2025},
  eprint = {2512.10004},
  archivePrefix = {arXiv},
  url    = {http://arxiv.org/abs/2512.10004v2}
}

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