DS$^2$-Instruct: Domain-Specific Data Synthesis for Large Language Models Instruction Tuning

Ruiyao Xu, Noelle I. Samia, Han Liu
3/13/2026
cs.CL

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Abstract

Adapting Large Language Models (LLMs) to specialized domains requires high-quality instruction tuning datasets, which are expensive to create through human annotation. Existing data synthesis methods focus on general-purpose tasks and fail to capture domain-specific terminology and reasoning patterns. To address this, we introduce DS$^2$-Instruct, a zero-shot framework that generates domain-specific instruction datasets without human supervision. Our approach first generates task-informed keywords to ensure comprehensive domain coverage. It then creates diverse instructions by pairing these keywords with different cognitive levels from Bloom's Taxonomy. Finally, it uses self-consistency validation to ensure data quality. We apply this framework to generate datasets across seven challenging domains, such as mathematics, finance, and logical reasoning. Comprehensive evaluation demonstrates that models fine-tuned on our generated data achieve substantial improvements over existing data generation methods.

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@article{xu2026dsinstruct,
  title  = {DS$^2$-Instruct: Domain-Specific Data Synthesis for Large Language Models Instruction Tuning},
  author = {Ruiyao Xu and Noelle I. Samia and Han Liu},
  year   = {2026},
  eprint = {2603.12932},
  archivePrefix = {arXiv},
  url    = {http://arxiv.org/abs/2603.12932v2}
}

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